Senior Werum PAS-X MES L2 Support & Integration Specialist

This is a remote position.

We are looking for an experienced Werum PAS-X MES L2 Support & Integration Specialist to join a global pharmaceutical manufacturing environment. The successful candidate will be responsible for supporting and maintaining the Werum PAS-X Manufacturing Execution System (MES), ensuring stable manufacturing operations, resolving production issues, and supporting integrations with enterprise systems.

This role is ideal for professionals with strong experience in MES production support, PAS-X administration, SAP integration, validation, and pharmaceutical manufacturing processes.

Key Responsibilities

• Provide Level 2 application support for Werum PAS-X MES across manufacturing and packaging operations.
  
• Monitor, troubleshoot, and resolve MES production incidents, execution failures, and interface issues within agreed SLAs.
  
• Perform root cause analysis (RCA) for recurring issues and coordinate resolutions with L3 support teams, vendors, and business stakeholders.
  
• Administer Werum PAS-X including user management, security roles, permissions, and system configuration.
  
• Support the complete Master Batch Record (MBR) and Electronic Batch Record (EBR) lifecycle, including deployment, updates, and maintenance.
  
• Ensure reliable integration between Werum PAS-X and enterprise systems, particularly SAP PP-PI, while supporting interface troubleshooting.
  
• Collaborate with Manufacturing, Quality Assurance, Validation, and IT teams to maintain compliant MES operations.
  
• Support system validation activities in accordance with GxP, CSV, and pharmaceutical regulatory requirements.
  
• Participate in change management, system enhancements, releases, and continuous improvement initiatives.
  
• Maintain technical documentation, SOPs, knowledge articles, and operational procedures.
  
• Support production during critical manufacturing activities and provide timely resolution of business-critical issues.
  

Requirements

Must Have

• 5+ years of experience supporting Werum PAS-X MES in a pharmaceutical or life sciences environment.
  
• Strong experience providing L2 application support for Manufacturing Execution Systems.
  
• Hands-on experience with Werum PAS-X administration.
  
• Experience managing Master Batch Records (MBR) and Electronic Batch Records (EBR).
  
• Strong knowledge of MES integration, particularly with SAP PP-PI (mandatory).
  
• Experience troubleshooting MES interfaces, production execution issues, and system integrations.
  
• Understanding of pharmaceutical manufacturing processes and GMP-regulated environments.
  
• Experience with incident management, root cause analysis, and production support.
  
• Familiarity with validation processes (CSV), GxP, and change control.
  
• Excellent analytical and problem-solving skills.
  

Nice to Have

• Experience with manufacturing automation environments.
  
• Knowledge of ISA-95 manufacturing architecture.
  
• Experience with integration technologies and middleware.
  
• Exposure to manufacturing systems including SCADA, PLCs, or historian platforms.
  
• ITIL knowledge or certification.
  

Preferred Background

Candidates with experience in:

• Pharmaceutical Manufacturing
  
• Life Sciences
  
• Biotechnology
  
• GMP-Regulated Production
  
• Manufacturing Automation
  
• Digital Manufacturing / Industry 4.0
  

Benefits

• Location: Remote in Europe
  
• Contract Type: Freelance / Contract
  
• Start date: June/July, 2026
  
• Time Allocation: 40 hours/week
  
• Global Pharmaceutical Company in Prague