Chief of Staff

Job Family: Administrative Support

Managerial Responsibilities: Yes

Classification:  Exempt / Full-Time

 #LI-Remote

GENERAL SUMMARY:

The Chief of Staff is considered a senior leader and a force multiplier for the entire Executive Leadership Team (ELT). This role is a trusted operating partner to the CEO, part driver of execution and accountability across the executive team, and part leader of the administrative function that supports the C-Suite. The Chief of Staff owns Vyne's enterprise operating cadence — translating strategy into resourced, sequenced plans; running the rhythms (ELT, board, town halls, offsites, planning cycles); driving cross-functional initiatives to closure; and ensuring the CEO and exec team operate at maximum leverage. The Chief of Staff also leads and develops the administrative team, ensuring the C-Suite is supported with the discipline, judgment, and quality the business requires.

DUTIES & RESPONSIBILITIES:

CEO Strategic Partnership & Enablement

• Serve as the CEO's principal operating partner and trusted advisor — anticipating needs, surfacing risks, and recommending action.
• Act as a thought partner on enterprise priorities; pressure-test ideas, frame decisions, and bring structure to ambiguous problems.
• Exercise delegated decision-making authority on day-to-day operational matters, escalating only what genuinely requires the CEO.
• Manage the CEO's strategic time horizon — protecting space for what matters most and ensuring follow-through on every commitment.

Executive Team Coordination & Operating Cadence

• Own the enterprise operating system: ELT meetings, executive offsites, leadership planning sessions, and the annual/quarterly planning cycle.
• Build and maintain the cadence of accountability — from priority setting through execution review — so commitments turn into results.
• Translate strategy into clearly sequenced, resourced operating plans the executive team can execute against.
• Drive disciplined decision-making practices: clear agendas, pre-reads, decisions captured, owners named, follow-through tracked.
• Serve as a connector and integrator across functions, removing friction between teams and ensuring initiatives don't stall at the seams.

Cross-Functional Execution & Special Projects

• Lead high-priority, cross-functional initiatives end-to-end — from framing through delivery — particularly those that span multiple ELT members.
• Apply structured problem-solving (research, analysis, scenario modeling, recommendations) to bring clarity and pace to complex decisions.
• Proactively identify execution gaps and operational bottlenecks; design and implement the fix in partnership with the accountable function.

Board, PE Sponsor & Stakeholder Management

• Partner with the CEO and CFO on board and PE sponsor preparation: cadence, narrative, materials, and follow-up.
• Drive production of board decks, value-creation updates, and long-range plans — owning quality, consistency, and timeliness.
• Manage executive-level external interactions where appropriate (key customers, partners, investors) on the CEO's behalf.
• Serve as a credible representative of the CEO and ELT in cross-functional and external settings.

Communications & Organizational Alignment

• Oversee communications flowing from the Office of the CEO — ensuring messaging is strategic, timely, clear, and consistent.
• Partner with People, Marketing, and ELT members to drive alignment between strategy and what employees see, hear, and act on.
• Lead preparation for All-Hands/Town Halls, leadership communications, and key internal moments.
• Translate complex strategic content into communications that move people to action.

Administrative Team Leadership

• Lead, coach, and develop Vyne's administrative team — currently the Executive Assistant and Administrative Assistant supporting the C-Suite.
• Establish service standards, coverage models, and operating practices that scale with the business.
• Set clear performance expectations, provide ongoing feedback, and create development paths for each team member.
• Ensure consistent, high-quality executive support across all C-Suite leaders, including calendar, travel, expense, and meeting orchestration.
• Own the CEO’s calendar end-to-end: scheduling, prioritization, meeting prep, briefings, and follow-ups.
• Balance complex, multi-executive calendars against short-term demands and long-term priorities.

Data, Insight & Reporting

• In partnership with the data and finance teams, build and maintain CEO/ELT-level dashboards and KPI reporting.
• Own regular performance reporting against strategic goals and OKRs; surface variances, risks, and recommended actions.
• Bring data and analytical rigor to decisions and recommendations — separate signal from noise.

Experience

• 10+ years of progressive professional experience, with at least 5+ years in a Chief of Staff, COO, GM, VP of Operations, or comparable senior operating role.
• Demonstrated experience operating inside the executive team of a mid-sized company (200–1,500 employees), ideally B2B SaaS, healthcare technology, or RCM/clearinghouse.
• Direct experience supporting and partnering with a CEO; a track record of being trusted with sensitive enterprise priorities.
• Proven ability to lead cross-functional initiatives from ambiguity to measurable outcome — execution chops, not just strategy frameworks.
• Experience with board and/or PE sponsor environments: preparing materials, managing cadence, navigating governance.
• Prior management experience, including building and developing a small team.