Senior Computational Research Scientist

The Department of Chemical Biology and Therapeutics (CBT) is seeking a highly motivated computational chemist interested in using state-of-the-art techniques in computer-aided drug design, virtual screens, and structure-guided drug design to discover novel small molecule modulators of targets relevant to pediatric disease. The applicant is expected to work alongside domain experts in the biology of pediatric disease, chemists, and pharmacologists, as well as the various institutional shared resources devoted to translational science, in a collaborative project team environment.

The applicant must have a strong background in computational chemistry, including molecular dynamics simulations, molecular docking, pharmacophore modeling, quantitative structure activity relationship modeling, and chemical informatics. The applicant must also be comfortable using high performance computing resources; and developing, maintaining, and mining chemical and biological databases. Proficiency in scientific computing languages, such as R and python, and open-source programing tools such as Knime, RDKit, and ChemProp is a plus.

Job Responsibilities:

• Lead computationally focused scientific research projects with minimal supervision from their PI. Develop new computational methods.
• Identify, process, organize, interpret, review, and report relevant data.
• Direct data collection.
• Present research to colleagues within and outside the institution; draft a complex manuscript with minimal supervision, as required.
• Regularly train and oversee the work of others in computational research and procedures.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

Minimum Education and/or Training:

• Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field.
• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree and 7+ years of relevant experience.
• Experience Exception: Master's degree and 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
• Rough criteria for this position based on publication output: 1-2 first author papers IF > 10 (or equivalent contribution to other research outputs).
• Prior experience in computational research techniques and processes.
• Proven performance in earlier role/comparable role.

Compensation

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