We are sharing a specialised part-time consulting opportunity for experienced preclinical R&D scientists with hands-on expertise in antibody-drug conjugates (ADCs), bispecific or multispecific antibodies, and in-house drug development.
This role supports a research initiative focused on improving how advanced computational systems reason about real-world biologics discovery and preclinical development. Selected experts will review scientific materials and programme data, evaluate technical outputs, contribute practical judgement on modality and development decisions, and help define high-quality data structures grounded in authentic ADC and bispecific R&D workflows.
Key Responsibilities
ADC & Bispecific Programme Review
-
Review technical materials and scientific data from ADC, bispecific, and multispecific antibody programmes
-
Evaluate whether analyses and conclusions reflect realistic preclinical development practice
-
Identify weak assumptions, unsupported claims, and biologically implausible outputs
-
Apply hands-on programme experience to complex development scenarios
-
Assess trade-offs involving efficacy, safety, developability, manufacturability, and programme risk
Target & Modality Strategy
-
Evaluate target-selection and modality-selection decisions
-
Assess biological rationale, therapeutic hypothesis, and competitive differentiation
-
Review trade-offs between ADC, bispecific, multispecific, and other biologic approaches
-
Identify risks associated with target biology, expression patterns, mechanism of action, or therapeutic window
-
Apply practical judgement to programme progression and prioritisation decisions
ADC Development
-
Contribute expertise across antibody selection, linker strategy, payload choice, conjugation, and overall ADC design
-
Evaluate potency, selectivity, internalisation, stability, exposure, and toxicity considerations
-
Review development decisions affecting efficacy and therapeutic index
-
Assess preclinical evidence supporting candidate progression
-
Identify common failure modes and optimisation challenges in ADC programmes
Bispecific & Multispecific Antibodies
-
Review programmes involving bispecific or multispecific antibody architectures
-
Evaluate target combinations, binding strategy, format selection, and functional activity
-
Assess developability, PK/PD, immunogenicity, safety, and manufacturability considerations
-
Review translational evidence and candidate-selection decisions
-
Identify modality-specific risks that may affect progression toward the clinic
Preclinical & Translational Development
-
Apply experience across in vitro, in vivo, translational, pharmacology, and PK/PD workflows
-
Evaluate experimental design and interpretation of preclinical evidence
-
Assess how findings influence candidate optimisation and development strategy
-
Review programme readiness for lead optimisation or IND-enabling development
-
Identify evidence gaps, unresolved risks, and appropriate next-stage studies
Cross-Functional R&D Expertise
-
Contribute expertise from areas such as:
-
Discovery biology
-
Medicinal chemistry
-
Protein and antibody engineering
-
Computational drug discovery
-
In vivo and translational research
-
Pharmacology and PK/PD
-
Toxicology
-
CMC and formulation
-
Apply cross-functional judgement to integrated programme decisions
-
Evaluate how findings from different disciplines affect candidate selection and development
Scientific Data Evaluation
-
Label, classify, and annotate scientific data and technical outputs
-
Identify meaningful experimental signals, development decisions, and failure modes
-
Evaluate the relevance and quality of information used in downstream research workflows
-
Help establish consistent standards for scientific review and annotation
-
Translate practical R&D expertise into structured, usable data
Dataset & Research Development
-
Help define structure and quality standards for scientific data pipelines
-
Identify which experimental and development variables should be captured
-
Surface workflow details that are often missed outside hands-on preclinical R&D
-
Participate in expert discussions, interviews, and research engagements
-
Provide practical perspective on how biologics programmes are advanced in industry
Ideal Profile
-
5+ years of relevant pharmaceutical or biotechnology R&D experience, with flexibility for candidates demonstrating exceptional technical depth
-
Hands-on, non-administrative preclinical R&D experience within a company developing its own therapeutic assets
-
Direct professional experience with ADCs and/or bispecific or multispecific antibodies
-
Experience at an organisation that has advanced internal drug programmes toward or into clinical development
-
Current or recent work in a core R&D function such as discovery biology, medicinal chemistry, protein or antibody engineering, computational discovery, translational science, pharmacology, PK/PD, toxicology, or CMC
-
Strong understanding of biologics discovery, optimisation, and preclinical development
-
Experience advancing a programme through lead optimisation, IND-enabling studies, or preclinical development is highly valued
-
Experience within mid-sized, emerging, or resource-constrained biotechnology environments is advantageous
-
Seniority may range from experienced individual contributor through Director level
-
Strong scientific judgement and ability to explain development decisions clearly
-
This opportunity is best suited to hands-on drug-development professionals rather than backgrounds focused primarily on CRO/CDMO services, academic-only research, QC/analytical functions, clinical development, diagnostics, regulatory affairs, or medical writing
Engagement Details
-
Part-time independent contractor engagement
-
Fully remote
-
Expected commitment of approximately 10 hours per week
-
Ongoing engagement based on project needs
-
Compensation: $50–$90/hour
-
Contributors will interact directly with the assigned research team
-
Projects may be extended, shortened, or concluded based on project needs and performance
-
Work must be completed without using confidential or proprietary information belonging to any employer, client, institution, or other third party
-
H1-B and STEM OPT support is unavailable for this engagement
About the Platform
This opportunity is available through 24-MAG LLC. We connect experienced professionals with remote consulting opportunities across technical, evaluation, and project-based workstreams.
By submitting this application, you acknowledge that your information may be processed by 24-MAG LLC for recruitment and opportunity matching in accordance with our Privacy Policy: https://www.24-mag.com/privacy-policy.
