Key Facts

Remote From:

Full time

Senior (5-10 years)

English

Hard Skills

Clinical Trial Planning Signal Handling Pharmacovigilance Cost Benefit Analysis Regulatory Compliance Patient Safety Global Project Management Regulatory Compliance Customer Engagement gRPC +14 more

Other Skills

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Business Proposals
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Quality Control
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Leadership
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Communication
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Team Management
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Team Building

Roles & Responsibilities

Degree in Life Sciences, Pharmacy, or related field
10+ years’ Pharmacovigilance experience with strong focus on Clinical Safety and global clinical trials
Proven leadership experience managing global teams, projects, and client delivery (CRO/pharma preferred)
Strong expertise in clinical trial safety, signal detection, and benefit-risk assessment

Requirements:

Lead and manage Clinical Safety teams across global projects
Oversee clinical trial safety activities including SAE/SUSAR management and safety data review
Ensure delivery of high-quality, compliant clinical safety services
Act as senior client contact and trusted advisor

Job description

This is a remote position.

About Arriello:

At Arriello, we provide a full range of Pharmacovigilance, Quality & Compliance, and Regulatory Affairs services to global pharmaceutical and life sciences companies. With a team of experienced professionals, we support our clients in meeting their regulatory obligations, maintaining product quality and patient safety, and navigating complex global compliance landscapes.

As a growing business with a dynamic culture, we are committed to high-quality delivery, continuous improvement, and creating an environment where people can thrive.

At Arriello, our values define how we work — and who we are:

Inclusive - We value equity, inclusion and dignity for all, recognising that we learn from each other every day.

Dedicated - We challenge the status quo to deliver pragmatic, tailored solutions for our clients.

Innovative - We collaborate closely—with our clients, colleagues and partners—to proactively find better ways forward.

Passionate - We build strong relationships based on empathy, respect and a genuine commitment to delivering quality in everything we do.

Senior Global Clinical Safety Manager

We are seeking an experienced Senior Global Clinical Safety Manager to join our Clinical Safety leadership team on a 2-year fixed-term contract, driving the delivery of global clinical trial safety services.

About the role:

In this role, you will oversee Clinical Safety teams delivering complex global projects, ensuring high-quality, compliant safety services. You will combine technical expertise with leadership and client engagement, playing a key role in shaping and growing our Clinical Safety offering.

Key responsibilities:

• Lead and manage Clinical Safety teams across global projects

• Oversee clinical trial safety activities including SAE/SUSAR management and safety data review

• Ensure delivery of high-quality, compliant clinical safety services

• Support resource planning, team development, and performance management

• Act as senior client contact and trusted advisor

• Support business development, including proposals and client discussions

• Drive continuous improvement across clinical safety processes

Requirements

• Degree in Life Sciences, Pharmacy, or related field

• 10+ years’ Pharmacovigilance experience with strong focus on Clinical Safety and global clinical trials

• Proven leadership experience managing global teams, projects, and client delivery (CRO/pharma preferred)

• Strong expertise in clinical trial safety, signal detection, and benefit-risk assessment

• In-depth knowledge of ICH, GCP, GVP, CIOMS and global regulatory requirements

• Experience delivering and overseeing key clinical safety documents (e.g. SMPs, IBs, DSURs)

• Demonstrated ability in resource planning, KPI delivery, and risk management across complex programs

• Strong stakeholder management, business development exposure, and audit/inspection readiness experience

Benefits

Work remotely while contributing to a global life sciences consultancy .
Lead quality operations that directly influence patient safety and regulatory compliance.
Collaborate in a multicultural, inclusive, and innovative environment.
Enjoy opportunities for career progression, professional development, and international exposure.
Flexible Work Options : Remote working flexibility to support your lifestyle.
Generous Time Off: Enjoy 5 weeks of holiday plus national holidays and 3 personal days to recharge.
Home Office Support: Get support to create a productive home office setup.
Bonuses: Benefit from an annual bonus program, spot bonuses, and employee-nominated recognition.

Arriello is an Equal Opportunity Employer. We are committed to creating a diverse, inclusive, and respectful workplace where all individuals are valued and treated with dignity. We encourage applicants from all backgrounds, including but not limited to race, colour, religion, gender, gender identity, sexual orientation, age, disability, national origin, or any other characteristic protected by law.

In line with our commitment, we provide reasonable accommodations to applicants with disabilities throughout the hiring process. If you require any accommodation, please contact us at recruitment@arriello.com .