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PK/PD Senior Scientist

Role overview

Qualifications

  • PhD in pharmacology, pharmaceutical sciences, biochemistry, or related field
  • 2-4 years of post-doctoral experience in pharmaceutical development (highly desirable)
  • DVM DACVCP or DVM Dipl. ECVPT (highly desirable)
  • Proven ability to design, analyze and interpret in vivo PK and PK/PD studies; experience with PK/PD modeling software such as WinNonlin, Monolix or Watson

Responsibilities

  • Design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports
  • Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens
  • Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects
  • Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid translation, measurement of target engagement, and dose regimen predictions

About the company

Zoetis logo

Zoetis

Pharmaceutical Manufacturing

The world’s leading animal health company. Zoetis is driven by a singular purpose: to nurture our world and humankind by advancing care for animals. We’ve been innovating ways to predict, prevent, detect, and treat animal illness for over 70 years, and we continue to stand by those raising and caring for animals worldwide – from veterinarians and pet owners to livestock farmers. Our leading portfolio and pipeline of medicines, vaccines, diagnostics and technologies make a difference in over 100 countries. Community Guidelines: This page is intended for learning more about how Zoetis is advancing care for animals. We aspire to create a supportive community, but there are some guidelines to which posts and comments on this page must adhere. If your post references a side effect related to any Zoetis product, we may contact you for more information. To monitor the safety of Zoetis products, we advise you to call our Veterinary Medical Information and Product Support Team at 1-888-963-8471; Support Team is available Mon-Fri 9am to 6:30pm ET. We reserve the right to remove any post/comment that violates LinkedIn Guidelines. We respectfully request that you refrain from posting comments including: Unsolicited and/or unverified medical advice Vulgarity and/or profanity Discriminatory and/or derogatory comments, hate speech Politics and religion Personal attacks and/or threats Promotion of illegal activity Copyright/trademark infringements Topics that may be considered spam/advertising Our regular business hours are Mon-Fri 9am to 5pm ET. Zoetis does not endorse and is not responsible for information and opinions shared by community members. The information shared is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. Testimonials represent individual experience only and the experiences and opinions of community members may be unique to the speaker. Terms of Use: https://www.zoetis.com/terms-of-use

Company details

Company typeXLarge
IndustryPharmaceutical Manufacturing
Company size10001

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Job description

Zoetis, a global leader in animal health, seeks an enthusiastic colleague to join our Veterinary Medicine Research and Development (VMRD) PK/PD Team to discover and develop novel therapeutics for veterinary medicine. The successful candidate will be primarily responsible for designing, conducting, analyzing, and interpreting in vivo PK/PD studies in multiple species in support of projects from early research through late-stage development. This position will require a highly motivated and independent individual who can effectively collaborate with other team members to advance projects. 

POSITION RESPONSIBILITIES:

  • Design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
  • Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
  • Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects.
  • Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions.
  • Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project.
  • Present research results to scientific teams, management, and regulatory agencies.
  • Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

REQUIRED EDUCATION AND EXPERIENCE:

  • Ph.D in pharmacology, pharmaceutical sciences, biochemistry, or related field.  2-4 years of post-doctoral experience in pharmaceutical development is highly desirable. DVM DACVCP or DVM Dipl. ECVPT is highly desirable.
  • Proven ability to design, analyze and interpret in vivo PK and PK/PD studies.  Experience with biotherapeutics (protein therapeutics) is highly desirable.
  • Skilled in the use of PK and PK/PD analysis software such as WinNonlin, Monolix or Watson.
  • Must have excellent verbal & written communication skills.
  • Self-starter, able to prioritize work and work efficiently with minimal supervision.
  • Working knowledge of bioanalytical methodology.
  • Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software is highly desirable.

The US base salary range for this full-time position is $114,000- $185,000. Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the base pay target range for new hire salaries for the position. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training.

 

This position is also eligible for short-term incentive compensation

This position is also eligible for long-term incentives

 

In addition to compensation, Zoetis offers a comprehensive benefits package that supports the physical, emotional and financial wellbeing of our colleagues and their families including healthcare and insurance benefits beginning on day one, a 401K plan with a match and profit-sharing contribution from Zoetis, and 4 weeks of vacation.

 

Visit zoetisbenefits.com to learn more.

 

 

Full time

 

 

Regular

 

 

Colleague

 

 

Any unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.

Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search.

 

 

Notice: Zoetis Recruiters will contact candidates via email from an address ending in @zoetis.com and may also initially connect with candidates through LinkedIn, including LinkedIn InMail. Zoetis does not use Gmail, Outlook, Yahoo, or other web-based/generic email domains to communicate about job opportunities, interviews, or offers of employment. If you receive a recruitment-related email message claiming to be from Zoetis that does not come from @zoetis.com, please treat it as suspicious. For your security, do not reply, click links, open attachments, share personal or financial information, or send money in response to unexpected or questionable recruitment communications.

 

 

Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of “@zoetis.com”. In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

 

 

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