Senior Toxicologist (REMOTE ROLE)

SENIOR TOXICOLOGIST

To support ICF’s dynamic growth and expanding client base, we are seeking a Senior Toxicologist to work in our Health Science Portfolio. This group of 100+ science professionals provide toxicology, hazard assessment, epidemiology, risk assessment, exposure assessment, environmental modeling, and related support that addresses the full spectrum of potentially hazardous agents, including chemicals and microbes. We specialize in identifying and quantifying the effects of environmental pollutants—including metals, pesticides, industrial chemicals, and volatile organic compounds—on human health and the environment.

The Senior Toxicologist’s project work would support federal agencies (such as U.S. EPA and NIEHS) in the design, conduct, and reporting of hazard studies and human health risk assessments for environmental pollutants. In particular, the successful candidate will provide leadership in the identification, interpretation, and integration of molecular biology, mechanistic toxicology, and new approach methodologies (NAMs) data to support hazard identification, mode-of-action analyses, systematic review, and human health risk assessments.  The role will involve evaluating diverse evidence streams including gene expression, -omics, cellular and molecular assays, pathway-based data, and adverse outcome pathway (AOP) frameworks.  

Location: Remote

What you’ll do 

• Project management and technical leadership activities on multiple projects concurrently involving toxicology data, systematic literature reviews, and risk assessment. Assist in the definition of project scope and objectives and serve as the primary point of contact for client and internal project teams.
• Toxicological report development, including writing methods, results, and discussion sections, reviewing toxicological conclusions based on the test results, and synthesizing findings into a weight of evidence analysis.
• Draft protocol and guidance documents, toxicological reports, manuscripts, project descriptions, and proposals.
• Collaborate with multidisciplinary teams of toxicologists, biologists, epidemiologists, and statisticians to address complex scientific and regulatory questions.
• Toxicology systematic review tasks including literature screening, study quality evaluation, study data extraction, dose-response analysis, incorporation of NAMs and mechanistic data, and data synthesis.
• Supervise, mentor, and train junior- and mid-level staff.

Basic Qualifications:

• Ph.D. in toxicology, pharmacology, environmental science, or related subject with 5+ years of experience in academic, industry, regulatory, or consulting fields.
• OR Master’s degree in toxicology, pharmacology, environmental science, or related subject with 10+ years of experience.

Preferred Qualifications:

• Strong working knowledge of mechanistic toxicology and molecular biology
• Experience integrating mechanistic, animal, and human evidence into a weight-of-evidence evaluation
• Experience with mode of action and adverse outcome pathway (MOA and AOP) concepts, frameworks, and analyses
• Experience evaluating molecular, cellular, and mechanistic data including transcriptomics, proteomics, metabolomics, and high-throughput screening assays
• Experience with endocrine disruptors, PFAS, PAHs, and other emerging contaminants
• Experience in cancer assessment
• Experience with NAMs, molecular biology techniques, and mechanistic data for regulatory decision-making
• Experience with systematic literature review
• Strong quantitative skills with experience in dose-response analysis, benchmark dose modeling, pathway enrichment analyses, or similar modeling experience
• Strong written and oral communication skills
• Proactive and problem-solving approach to challenges
• Experience/familiarity with government programs
• Excellent organizational skills and attention to detail
• Ability to prioritize, multi-task, and work under strict deadlines in a fast-paced environment
• Experience with project management and staff leadership
• Demonstrated ability to formulate and execute technical approaches to solving scientific questions 

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Bot and Third-Party Applications

Please note that this application must be submitted directly by the applicant for consideration. Failure to do so may result in the application being excluded for consideration.  Applicants needing an accommodation for disability or religious purposes in connection with the application process should contact Candidateaccommodation@icf.com for assistance.

Working at ICF

We can only solve the world's toughest challenges by building a workplace that allows everyone to thrive. We are an equal opportunity employer. Together, our employees are empowered to share their expertise and collaborate with others to achieve personal and professional goals. For more information, please read our EEO policy.

We will consider for employment qualified applicants with arrest and conviction records.

Reasonable Accommodations are available, including, but not limited to, for disabled veterans, individuals with disabilities, and individuals with sincerely held religious beliefs, in all phases of the application and employment process. To request an accommodation, please email Candidateaccommodation@icf.com and we will be happy to assist. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations.  

Read more about workplace discrimination rights or our benefit offerings which are included in the Transparency in (Benefits) Coverage Act. 

At ICF, we are committed to ensuring a fair interview process for all candidates based on their own skills and knowledge. As part of this commitment, the use of artificial intelligence (AI) tools to generate or assist with responses during interviews (whether in-person or virtual) is not permitted. This policy is in place to maintain the integrity and authenticity of the interview process.  

However, we understand that some candidates may require accommodation that involves the use of AI. If such an accommodation is needed, candidates are instructed to contact us in advance at candidateaccommodation@icf.com. We are dedicated to providing the necessary support to ensure that all candidates have an equal opportunity to succeed.  

Pay Range - There are multiple factors that are considered in determining final pay for a position, including, but not limited to, relevant work experience, skills, certifications and competencies that align to the specified role, geographic location, education and certifications as well as contract provisions regarding labor categories that are specific to the position.

The pay range for this position based on full-time employment is: