Senior Sales Manager (On-Premise Hospitality)

About the Role

ZBiotics is hiring its first dedicated hospitality leader to build our on-premise channel from the ground up.

We’ve seen strong early proof that hospitality — bars, restaurants, hotels, nightlife groups, and tastemaker venues — can become both a meaningful revenue channel and one of our most powerful brand engines. Pre-Alcohol belongs in the places and moments people plan their nights around. The right accounts don’t just drive volume; they create credibility, cultural relevance, and awareness that compounds across every other channel.

We’re not trying to be everywhere. We’re trying to show up in the places that matter. With early wins in marquee accounts, we’ve validated the opportunity. Now we’re ready to scale it with dedicated ownership.

You’ll own the channel number from day one: building the pipeline, closing priority accounts, securing menu placements, earning buy-in from operators and staff, managing reorders, and expanding successful accounts into multi-location opportunities. The role starts hands-on in the field, personally landing the accounts that set the standard, then building the ambassador network and playbook to scale across priority markets.

This is a rare chance to build a channel, not just manage one. It’s for someone who is energized by building, trusted in premium hospitality environments, and knows how to turn great relationships into real account growth.

About ZBiotics

At ZBiotics, we make genetically engineered probiotics that improve daily life. Our mission is to create, brand, and sell GMOs that people love. As a group of motivated, yet down-to-earth people, we are fueled by two things: a love for science and a commitment to being people-first. GMO products like ours — designed to benefit individuals who use them directly — are the future.

As the first to market, we believe it’s our duty to set a high bar for product quality, safety, and transparency for others to follow.

In 2019, we launched the world’s first genetically engineered probiotic: ZBiotics® Pre-Alcohol, a 14mL probiotic drink designed to break down an alcohol byproduct that leads to rough mornings after drinking. Since then, ZBiotics’ business has continued to grow rapidly year over year. We’ve sold over 10 million bottles of Pre-Alcohol, with over half those bottles coming in 2025 alone. And in 2024, we launched our second product: ZBiotics® Sugar-to-Fiber, a genetically engineered probiotic that creates fiber from the sugar you already eat, contributing to microbiome health.

ZBiotics is headquartered in San Francisco and backed by venture investors including Y Combinator, Spring Tide Capital, and Khosla Ventures, among others.

Your Responsibilities

The following are essential functions to this role:

• Close the marquee accounts. As a player-coach, directly close and steward the highest-value whale accounts, groups, and multi-location opportunities that set the standard for the channel and open doors for the rest of the team.
• Build the hospitality playbook. Turn what works in the field into repeatable systems ambassadors can use: pitch materials, account qualification criteria, launch checklists, staff training scripts, objection handling, and reorder tracking.
• Build and scale the ambassador network. Take over an early-stage ambassador program and develop it into a high-performing field network. Recruit, onboard, coach, and manage commission-based Hospitality Ambassadors across priority markets (Los Angeles, San Francisco, New York, Miami, and Chicago). Set the named-account approach and coverage map, develop talent, and manage performance. Ambassadors report to and are developed by this role.
• Own the channel's number and operating cadence. Carry the on-premise revenue target and the network's aggregate productivity: closes, account density, velocity, and reorders. Run the cadence (pipeline review, forecasting, and reporting) needed to hit it.
• Define what great account activation looks like. Set the standard for named menu placements, staff training, sampling, and service-flow execution, then equip every ambassador to replicate it and protect a consistent, premium brand presence.
• Build senior relationships across hospitality. Develop trust with owners, operators, beverage directors, GMs, hotel F&B leaders, and group buyers, and translate ZBiotics' brand and science into operator value: incremental revenue, attractive margin, guest experience, and low operational lift.
• Partner cross-functionally and keep clean reporting. Work with Brand, Creative, Retail Ops, Supply Chain, Finance, the in-house account team, and the broader Sales team to keep field execution brand-right and feasible. Maintain CRM and channel reporting that shows where the motion is working or breaking down.

About You

This role is for a sales-driven leader who knows how hospitality works and how to turn relationships, their own and their team's, into measurable commercial outcomes. You're credible in the field, persistent with follow-up, and energized by building a team and a channel from the ground up.

Desired qualifications are listed below. However, we recognize that ZBiotics is relatively unique in its position straddling biotechnology and consumer products, so even if your experience does not perfectly match the description below, but you're excited about the opportunity, please apply!

Desired Qualifications:

• 5+ years in on-premise beverage sales, hospitality sales, or premium CPG field sales, including building or leading field sales teams, ambassadors, or independent reps.
• A personal track record of closing on-premise accounts and growing their performance after launch: menu placements, staff adoption, reorders, and multi-location rollouts.
• Strong understanding of hospitality buying paths, menu placement, staff training, service flow, and reorder mechanics; able to sell and educate around a new category.
• Commercial fluency around pricing, margin, activation costs, sell-through, reorder rate, and account profitability.
• Comfort designing the systems that scale a field team: compensation, territory/account rules, qualification criteria, launch checklists, training scripts, and account review templates.
• CRM and pipeline discipline, with the reporting rigor to manage a network to its number; high judgment around premium brand presence and hospitality culture.
• Comfort operating in the field, traveling frequently, and managing a high-miss-rate sales process; strong written and verbal communication.
• Open-minded, adaptable, and flexible in their approach to problems and challenges.
• Kind and empathetic person.

Benefits

We believe in a life well-lived. ZBiotics offers competitive benefits for a life outside of work, including: health / dental, 401(k) matching, a flexible, unlimited paid time off PTO policy, 16 weeks fully paid parental leave, a home office stipend, transit benefits for those in the San Francisco Bay Area, and access to co-working office space if located in or visiting San Francisco.

The base salary for this position ranges between $150,000–$165,000 per year, depending on qualifications and experience. 

Location: New York City strongly preferred; candidates living in Los Angeles, Chicago, Miami or San Francisco are also encouraged to apply. Regular travel required.
Employment type: Full-time, salaried, exempt
 

Employment at ZBiotics is at-will.

We encourage you to apply …

At ZBiotics, we value our differences, and we encourage all — especially those whose identities are traditionally underrepresented in tech organizations — to apply.

ZBiotics is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, sexual orientation, and gender identity), national origin, age, disability, genetic information, veteran status, or any other protected characteristic under applicable federal, state, or local law.

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

ZBiotics will provide reasonable accommodations for qualified individuals with disabilities in the application and employment process. If you need assistance or accommodation, please contact ZBiotics HR at [email protected].