Senior Director, Head of Clinical Biomarkers
Job description
Your work will change lives. Including your own.
The Impact You’ll Make
Recursion is at the forefront of reimagining drug discovery and development through broadening the funnel of potential targets, using technology and standardization to build connected data. As Head of Clinical Biomarkers, you will manage a team of bioanalytical and biomarker scientists, and will be responsible for providing biomarker support for Recursion’s Clinical Development portfolio constituting ~10 programs in early development with a mix of oncology and rare disease indications. You will leverage your deep understanding of the scientific, regulatory and logistical aspects of biomarkers, to implement appropriate biomarker measurements that enable clinical decision making, and the development of safe and effective medicines to address unmet medical needs.
In this role, you will:
- Lead the clinical biomarker function at Recursion and ensure that clinical decisions are being informed by high quality biomarker data; represent the function at key leadership meetings
- Develop and implement fit-for-purpose biomarker strategies for programs entering the clinic by working closely with drug discovery functions
- Implement innovative, noninvasive technologies for the measurement of oncology biomarkers and explore ways to feed clinical data back into Recursion’s operating system
- Manage a group of biomarker and bioanalytical scientists and support their career development while ensuring high quality delivery on the portfolio
- Drive the development and qualification of predictive and pharmacodynamic biomarker assays by working with appropriate CROs
- Collaborate with data science functions to analyze and interpret biomarker data including omics datasets to enable clinical decision making
The Team You’ll Join
You will join the Development Sciences team, will report to the VP of Development Sciences, and will be part of the Clinical Development organization at Recursion. The Development Sciences team is a group of project-facing Translational scientists that supports the transition of projects from discovery into clinical development and beyond. Core functions within this team include translational PK/PD modeling, clinical pharmacology, clinical bioanalysis and biomarkers. This is a collaborative group of scientists who: 1) work closely with discovery to ensure the progression of the right molecule at the right dose for the right patient, 2) support IND filings, and 3) ensure the continued implementation of the appropriate translational strategies for projects in clinical development. In this role you will have the opportunity to work seamlessly with the drug discovery and clinical development organizations at Recursion to ensure that we apply the best science in service of the portfolio.
The Experience You’ll Need
- PhD with 10+ years or MS with 15+ years of experience as a biomarker and/or translational scientist in the biopharmaceutical industry
- Degree in biology, biochemistry, or related biomedical discipline
- Strong hands-on experience with clinical biomarker assay development and qualification; experience in an oncology setting preferred
- Extensive experience contributing as a senior biomarker scientist to clinical study teams including contributing to protocols, working closely with clinical operations on logistics, and with data science/bioinformatics groups on data analysis and interpretation
- Strong working knowledge of various platforms and technologies applied for the measurement of predictive and pharmacodynamic biomarkers including ‘omics technologies
- Knowledge of regulatory expectations (FDA and EMA) and industry's best practices in bioanalytical and biomarker/diagnostic assay method development and validation
- People management experience preferred
Working Location:
This position is ideally based at one of our offices located in Salt Lake City / New York City / Toronto. Please note that we are a hybrid environment and ask that employees spend 50% of their time in the office. We will also consider remote work for this position in the US or Canada. We ask that remote employees commit to regular on-site visits for routine work and departmental events.
#LI-CP1
At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is:
- Developing: $207,000
- Skilled: $230,000
- Expert: $253,000
To learn more about our level within levels, click here.
You will also be eligible for bonuses and equity compensation + our comprehensive benefits package for United States based candidates. The range displayed on each job posting reflects target ranges for US new hire salaries and is determined by job, level, and market factors.
During the interview selection process, you will connect with a Talent Acquisition Partner who will be your advocate and ally to ensure you receive the appropriate compensation that meets your needs for your skills, experience, and relevant education/training, while also reviewing our very competitive total rewards package.
The Values That We Hope You Share:
- We Care: We care about our drug candidates, our Recursionauts, their families, each other, our communities, the patients we aim to serve and their loved ones. We also care about our work.
- We Learn: Learning from the diverse perspectives of our fellow Recursionauts, and from failure, is an essential part of how we make progress.
- We Deliver: We are unapologetic that our expectations for delivery are extraordinarily high. There is urgency to our existence: we sprint at maximum engagement, making time and space to recover.
- Act Boldly with Integrity: No company changes the world or reinvents an industry without being bold. It must be balanced; not by timidity, but by doing the right thing even when no one is looking.
- We are One Recursion: We operate with a 'company first, team second' mentality. Our success comes from working as one interdisciplinary team.
Recursion spends time and energy connecting every aspect of work to these values. They aren’t static, but regularly discussed and questioned because we make decisions rooted in those values in our day-to-day work. You can read more about our values and how we live them every day here.
More About Recursion
Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in London, Toronto, Montreal and the San Francisco Bay Area. Learn more at www.Recursion.com, or connect on X (formerly Twitter) and LinkedIn.
Recursion is an Equal Opportunity Employer that values diversity and inclusion. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.
Recursion welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
Required profile
Experience
Other Skills
- People Management
- Problem Solving
- Collaboration
- Communication
- Leadership
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