LIMS Associate, Oncology

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a LIMS Associate to join our Laboratory Information Management Systems (LIMS) team in support of clinical patient testing in our high-throughput CLIA lab. The LIMS Associate will be responsible for (1) Coordinating tech transfer between the clinical lab and LIMS Engineers, (2) Triaging and responding to support tickets, and closing them out where possible, (3) monitoring LIMS usage patterns, trends, and issues in the lab and suggesting improvements to LIMS developers

This role will help to build upon the strong technology and execution found at BTO. This is considered an onsite role at our Menlo Park lab, with flexibility to work from home or at our Union City site when applicable.

Responsibilities:

• Collaborate closely with wet lab scientists in our clinical molecular biology lab to understand workflows and the corresponding data flow needs
• Perform routine LIMS systems and software maintenance procedures
• Collaborate with SMEs to design & implement LIMS workflows & to support new assay launches
• Work with the LIMS Administrator to manage existing LIMS workflows, their operations, lifecycle and data
• Manage full release process, including validation, coordination of training, completion of required documentation, and deployments
• In coordination with the LIMS Administrator, liaise with Semaphore Solutions, the external developer of the Labbit LIMS, and with other third party contractors & developers, as needed
• Monitor, troubleshooting, and correct systems and software technical issues (e.g. resolving bugs and LIMS outages)
• Triage & escalate unresolved technical issues to appropriate internal teams or external developers
• Network with internal stakeholders & customers to develop new technologies
• Develop and maintain relevant technical documentation (SOPs, Policies, etc) for use of BTO’s LIMS systems
• Create workflow diagrams and documentation of current and proposed lab processes
• Ensure compliance to all relevant corporate and regulatory requirements
• Collaborate with the LIMS Administrator to provide  end-to-end support & ownership for tickets requiring system change
• Train SMEs in Software Engineering, Data Science, and CLIA to understand LIMS API and data warehouse
• Onboard personnel to LIMS and define systems, roles, and responsibilities
• Assist in establishing scope of features based on goals and timelines
• Monitor KPIs for Labbit LIMS and work with LIMS Administrator and lab personnel to ensure timely progress toward company goals

Requirements:

• Bachelor's degree in Computer Science, Software or Information Systems or equivalent technical expertise with information systems
• Comfortable working with cross-functional teams across CLIA, Process Engineering, Software Engineering, Automation and Service Engineering, Data Science, Supply Chain, and Product
• Excellent ability to communicate with CLIA lab personnel to understand molecular biology workflows, regulatory compliance needs and real-world laboratory challenges
• 0-2 Years' Experience with Laboratory Information Systems (LIS) 
• 0-2 Years' Experience working in a CLIA Lab, medical device, or pharma environment
• Experience with diagramming workflows using tools such as Lucidchart, Visio, etc.
• Ability to troubleshoot and diagnose basic technical issues 
• Experience with Bash or similar shell environment
• Experience with Python
• Strong attention to detail and ability to work flexibly and well under given timeframes
• Highly organized, strong written and verbal communicator
• Excellent problem-solving and communication skills 
• Strong project management skills and familiarity with project management tools such as Jira, Notion, etc.

Nice-To-Haves:

• Experience with Illumina NGS workflows
• Experience with molecular biology workflows in a high-throughput environment
• Experience developing scripting solutions to automation problems in a fast paced/agile setting
• Experience with automated liquid handlers and software integrations
• Familiarity with AWS S3
• Familiarity with cloud applications and with EC2
• Familiarity with structured data types, including JSON
• Experience with REST APIs 
• Experience with the Labbit LIMS platform
• Direct experience with multiple LIMS products (Clarity, STARLIMS, Labvantage, Labworks, etc)
• Familiarity with Quality Management Systems such as Arena and with related regulations (CFR 21 Part 11, ISO 13485, etc) 
• Experience with data analysis using Excel, SQL, R, and/or Python
• Experience with ticket support in a production environment
• Experience with bioinformatics pipelines

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

The base salary range for this role is $76,155 to $87,034. This position is eligible for an annual bonus and receives a new hire equity grant of up to $20,000 at grant value, vesting over four years, plus annual equity refresh grants equal in value to the new hire grant. Together, the total four-year value of base, target bonus, and equity is up to approximately $433,000. We also offer competitive medical and dental coverage and a 401(k) with company match.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com