Role overview

Qualifications

Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline; M.D. with Clinical Pharmacology expertise; or PharmD with a Clinical Pharmacology fellowship, with 5–9+ years of biotech/pharmaceutical drug development experience
Proven track record leading all clinical pharmacology aspects of drug development, including PK/PK-PD analyses (non-compartmental, population PK, PK–PD modeling) to inform dose selection and exposure–response/safety analyses
Proficiency with modeling software (WinNonlin, Monolix, NONMEM, R) and ability to perform modeling and simulation; strong collaboration and regulatory submission experience
Oncology experience preferred but not required; demonstrated ability to work with cross-functional teams and regulatory bodies

Responsibilities

Develop and lead the clinical pharmacology and pharmacometrics strategies for a portfolio of rare disease and oncology programs; serve as Clinical Pharmacology lead and regulatory representative
Design clinical studies and provide clinical pharmacology input across all phases (Phase 1–3) and dedicated Phase 1 clinical pharmacology studies
Author and review clinical pharmacology sections for regulatory documents (Investigator's Brochures, INDs, NDAs) and act as the pharmacology expert during interactions with health authorities
Interface with cross-functional teams (clinical study teams, translational modeling and toxicology, preclinical, due diligence) and oversee or perform modeling and simulation to address drug development questions and accelerate decision making

Key facts

Remote from: United Kingdom
Full time
Senior (5-10 years)
English

Hard skills

Pharmacodynamics Population Model Pharmacology Winbatch Mono Toxicological Chemistry Clinical Study Design Biomarkers Pharmacokinetic Dosing Pharmacology Cross-Functional Collaboration Conflict Resolution Stakeholder Communications Social Influences

Other skills

Social Collaboration
Decision Making
Accountability
Adaptability
Leadership
Communication
Resourcefulness
Time Management
Teamwork

About the company

Recursion

Biotech: Biology + Technology

We are a clinical-stage biotechnology company decoding biology by integrating technological innovations across biology, chemistry, automation, data science and engineering to industrialize drug discovery. We are leveraging new technology to create virtuous cycles of learning around datasets to build the next-generation biopharmaceutical company. It’s complex biology, decoded. While we are united in a common mission, Decoding Biology to Radically Improve Lives, our greatest strength lies in our differences: expertise, gender, race, disciplines, experience, and perspectives. Deliberately building and cultivating this culture is critical to achieving our audacious goals. We are proudly headquartered in Salt Lake City.

Company details

Company typeScaleup

IndustryBiotech: Biology + Technology

Company size201 - 500

Links

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Job description

Your work will change lives. Including your own.

The Impact You’ll Make

You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs.

In this role, you will:

Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan. You’ll be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster.
Design clinical studies. You’ll provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies.
Author review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions. Act as the clinical pharmacology expert during interactions with health authorities.
Interface with cross-functional teams. You’ll work closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams and due diligence teams to ensure clinical pharmacology-related considerations are addressed.
Solve drug development questions/problems by overseeing and/or performing modeling and simulation with various tools to expedite decision making.

The Team You’ll Join

You will join the Development Sciences team within Recursion comprising clinical pharmacology, pharmacometrics, translational modeling and clinical biomarkers. The Development Sciences group sits within Recursion’s Clinical Development organization. Team members get to sit on both Discovery and Development projects and work in a seamless end-to-end environment at Recursion. The team collaborates closely with clinical development functions (clinical science, clinical operations, regulatory affairs, biostatistics, etc.), as well as discovery functions (DMPK, Biology, Chemistry and Translational Biomarkers).

The Experience You’ll Need

Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship, with 5-9+ years of experience in biotech/pharmaceutical drug development.
Demonstrated success leading all clinical pharmacology related aspects of drug development.
Ability to work closely with internal and external stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support dose selection, exposure-response and exposure-safety analyses through various phases of drug development.
Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software.
Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders
Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions and attending regulatory meetings.
Highly motivated, decisive, and results-oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company

Experience in oncology is preferred, but not an absolute requirement.

Working Location & Compensation:

Making London or Oxford (Milton Park) your home base is ideal; however, we will consider remote work for this position. We ask that remote employees commit to regular on-site visits for routine work and departmental events.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is £118,300 to £136,500. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.

#LI-REMOTE

#LI-DB1

The Values We Hope You Share:

We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust.
We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action.
We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection.
We move with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day.
We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy—leaders take accountability for decisive action, and teams own outcomes together.
We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities.

Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively.

More About Recursion

Recursion (NASDAQ: RXRX) is a clinical-stage TechBio company decoding biology to radically improve lives. Recursion is advancing a portfolio of differentiated investigational medicines across its wholly owned and partnered pipeline in oncology, rare disease, neuroscience, immunology, and other therapeutic areas with significant unmet need. Enabling its mission is the Recursion OS, an AI-native, end-to-end drug discovery and development platform integrating biology, chemistry, and clinical development into a unified intelligence system. Powered by proprietary multimodal data, purpose-built AI models, and bilingual teams fluent in both science and AI, the Recursion OS is designed to translate complex science into medicines that matter — faster, better, and at scale — for patients who are waiting.

Recursion’s platform infrastructure is anchored in Salt Lake City, Utah and Milton Park, Oxfordshire, where its automated biology and chemistry laboratories generate proprietary data at industrial scale. Recursion also maintains offices in New York, Montréal, and London, three global hubs for talent and leadership at the intersection of AI and scientific innovation. Learn more at www.recursion.com, or connect on X and LinkedIn.

Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.

Accommodations are available on request for candidates taking part in all aspects of the selection process.

Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.