Project Manager, Feasibility Site Activation

Project Manager FSA - Poland, Bulgaria, Czechia, Georgia, Hungary, Ireland, Latvia, Portugal, Romania, Serbia, Slovakia, Spain, UK - Homebased

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

About the role

At ICON plc, we are committed to improving and saving lives through clinical research. As a Project Manager – Feasibility & Site Activation, you will play a critical role in driving the successful start-up of global clinical studies.

This is a highly visible position where you will take ownership of the Study Start-Up (SSU) strategy and execution—ensuring that sites are activated efficiently, regulatory pathways are navigated effectively, and studies are positioned for successful delivery from day one.

You will work at the center of cross-functional collaboration, partnering with sponsors, internal teams, and sites worldwide to deliver start-up excellence at scale.

What You Will Be Doing

• Shape and execute Study Start-Up strategies across global, multi-country studies, ensuring alignment with timelines, scope, and sponsor expectations

• Lead the development and delivery of comprehensive Study Start-Up Plans, covering regulatory, ethics, and contract execution across all participating countries

• Drive end-to-end start-up activities from site identification through to IP release, maintaining momentum and accountability for key milestones

• Provide strategic input at Bid Defence and Kick-Off meetings, influencing study design and start-up feasibility from the outset

• Oversee regulatory and ethics submissions, ensuring high-quality, compliant, and timely approvals across regions

• Manage site contract and budget negotiations in collaboration with legal, finance, and sponsors, supporting timely site activation

• Proactively identify risks, dependencies, and bottlenecks, implementing mitigation and escalation strategies to protect study timelines

• Partner closely with Project Managers and cross-functional stakeholders, ensuring seamless integration of start-up within overall study delivery

• Ensure accuracy, quality, and inspection readiness of all study documentation, including oversight of CTMS and eTMF activities

• Lead and coordinate Study Start-Up team members, providing direction, support, and oversight to ensure consistent delivery

• Drive process consistency and continuous improvement across regions, contributing to operational excellence initiatives

• Maintain oversight of study metrics, budgets, and scope of work (SOW), ensuring delivery within agreed parameters

• Provide clear, structured reporting and updates to sponsors and internal leadership, enabling informed decision-making

• Contribute to a culture of performance, collaboration, and accountability aligned with ICON values

Your Profile

• Proven experience managing Study Start-Up (SSU), feasibility, or site activation activities within clinical research

• Experience working on global or multi-country clinical studies

• Strong knowledge of regulatory and ethics submission processes

• Experience coordinating site contracts and budgets

• Demonstrated ability to manage timelines, risks, and competing priorities

• Familiarity with CTMS, eTMF, and clinical trial systems

• Solid understanding of ICH-GCP and applicable regulatory frameworks

• Strong stakeholder management and communication skills

• Ability to collaborate effectively across cross-functional, global teams

• Structured, proactive, and solution-oriented approach

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What ICON can offer you:

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values.   We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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