340B regulatory manager

The Manager of Commercial Analytics – Regulatory Affairs & Health System Strategy plays a critical role in shaping VytlOne’s strategic response to an evolving healthcare regulatory environment. This position is responsible for monitoring regulatory developments and partnering closely with the Vice President of Health System Strategy & Analytics to identify headwinds and tailwinds impacting the business.

About VytlOne

Did you know that patients see their pharmacist an average of 12 times a year? Pharmacy is at the heart of healthcare. Come join VytlOne and make a direct impact on patients’ lives. Improve your own wellbeing with our robust benefits and flexible work environment. At VytlOne, you have a career with limitless possibilities and the charge to make a difference. A company of 1,000 diverse people and almost 100 years of pharmacy experience, we offer the stability of a Fortune 500 company with the energy and innovation of a startup. We provide services and technology that fuel the entire pharmacy ecosystem, but we are more than pharmacy services. We enable pharmacy care.

• Collaborate with the Director of Health System Strategy and cross-functional VytlOne teams to assess regulatory developments and their implications.
• Support Regional Vice Presidents and onsite VytlOne teams in managing and optimizing client 340B programs.
• Communicate regulatory and strategic impacts to internal and external stakeholders, including Executive Leadership Teams, through clear and actionable insights.
• Partner closely with analytics teams to define business requirements, interpret scenario‑based models, and apply insights to executive decision‑making (hands‑on technical execution not required but valued).
• Design and recommend mitigation or optimization strategies to promote compliance while delivering on commercial opportunities.
• Lead the development of client‑ready deliverables, guiding teams from problem definition through synthesis, storytelling, and final executive presentation, while maintaining consistency with strategic objectives and regulatory landscape.
• Create high-quality executive-ready presentations for leadership meetings, client discussions, webinars, and industry conferences.
• Monitor federal and state healthcare policy trends including 340B, IRA, and Medicaid developments.
• Lead and manage a team of remote employees while providing dotted-line support and guidance to onsite VytlOne team members to promote alignment, performance, and consistent execution.
• Promote and ensure compliance with VytlOne Business Code of Conduct, as well as other company policies and procedure.
• Serve as a visible expert and advisor on pharmacy pricing and regulatory matters (e.g., 340B, IRA, State Medicaid) and health system analytics, representing VytlOne in client engagements, industry forums, and internal leadership meetings.
• Drive continuous improvement in compliance, reporting, and operational outcomes for health system partners.
• Actively participate in strategic partnerships and optimization projects across diverse health system settings, collaborating with Health System Strategy leaders, 340B Execution Services managers, and account specialists.

• Bachelor’s degree from an accredited college or university required; advanced degree in Health Economics, Public Health, Public Policy, Business, or Analytics preferred.
• 5+ years in consulting or client-facing roles in healthcare, pharmacy services, or health system strategy, with a focus on regulatory and reimbursement issues.

• 5+ years in consulting or client-facing roles in healthcare, pharmacy services, or health system strategy, with a focus on regulatory and reimbursement issues.

• Proven ability to lead complex projects, develop assumptions, assess scenarios, and deliver results independently in changing environments.

• Demonstrated expertise in pharmacy and healthcare regulation, including 340B, Medicare, Medicaid, IRA, and related federal and state policy, with the ability to interpret evolving requirements and translate them into actionable business and client strategies.

• Proven experience advising senior health system leaders and executives, including regular presentation to C‑suite and Executive Leadership Teams, delivering clear, credible, and strategically grounded recommendations.

• Experience supporting, advising, or overseeing client 340B programs, including strategic design considerations, compliance risk assessment, optimization opportunities, and cross‑functional stakeholder alignment.

• Demonstrated ability to oversee, review, and elevate work products, ensuring fact-based assumptions, regulatory accuracy, and executive‑level quality across client‑facing deliverables such as presentations, models, briefing materials, and strategic recommendations.

• Exceptional strategic, critical thinking, and judgment, with the ability to anticipate regulatory headwinds and tailwinds, assess downstream impacts, and proactively recommend mitigation or growth strategies.

• Demonstrated leadership qualities, including mentoring and developing junior talent, setting expectations, providing coaching and feedback, and raising the overall quality and confidence of analytical and advisory outputs.

• Outstanding written and verbal communication skills, with the ability to distill complex regulatory, analytical, and strategic concepts into clear, executive‑ready narratives.

• Willingness and ability to travel approximately monthly to support client engagements, leadership meetings, and strategic initiatives.

At VytlOne we foster a diverse and progressive culture that promotes a work-from-home model and a "dress-for-your-day" approach to work attire. Our team-oriented environment encourages collaboration and innovation. We offer highly competitive compensation and comprehensive health benefits including:

• Comprehensive mental health and wellbeing resources
• Nationwide Blue Cross Blue Shield PPO with employee-friendly plan design, including a $850 individual annual medical deductible and $25 office visit copays, with low biweekly premiums
• Company-paid basic life/AD&D, short-term and long-term disability insurance
• Rx, dental, vision, other voluntary benefits, and FSA
• Employer-matched 401k Plan
• Industry-leading PTO plan
• And more!

VytlOne is an EOE, including disability/vets

Compensation range: Salary $120k to $150k annually.