Principal AI Scientist

Work set-up: 
Full Remote
Contract: 
Experience: 
Senior (5-10 years)
Work from: 

Offer summary

Qualifications:

PhD in Computer Science, Bioinformatics, or related field., Over 8 years of experience applying ML/AI in healthcare or life sciences., Proficiency in Python and deep learning frameworks like PyTorch or TensorFlow., Hands-on experience with integrating large language models and computer vision into production pipelines..

Key responsibilities:

  • Lead development of ML/AI models for translational research and drug development.
  • Collaborate with cross-functional teams including clinicians and engineers.
  • Design scalable ML pipelines on cloud platforms like AWS, ensuring data privacy and compliance.
  • Mentor junior team members and publish research in scientific venues.

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Natera Large http://www.natera.com
1001 - 5000 Employees
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Job description

Principal AI Scientist

Role Overview
We are seeking a technically deep, impactdriven MLAI Scientist with expertise in multimodal data (e.g., genomic, transcriptomic, clinical, andor imaging) to unlock transformative insights in precision medicine.

As a senior technical leader, you will:
Lead development of novel MLAI approaches for translational research and drug development
Bridge research innovation and production delivery alongside AI engineers, data scientists, clinicians, and product teams
Leverage unique, largescale multimodal datasets and highperformance computing infrastructure

Key Responsibilities

Model Research & Development
Select, finetune and optimize foundation models (e.g., LLMs, UNet, ViT, transformers, GNNs, diffusionembedding models for multimodal data)
Prototype and benchmark novel architectures for complex tasks across sequencing, imaging and clinical data
Build agentic systems to automate sophisticated workflows

Productionization & MLOps
Design and implement scalable, observable, and maintainable ML pipelines on AWS (SageMaker, EC2GPU, Lambda, ECSEKS)
Containerize models (DockerKubernetes), develop APIs or batch services, and integrate into CICD workflows
Contribute to reusable tooling (prompt libraries, feature extractors, evaluation harnesses) and highperformance retrieval strategies (vector DBs, RAG)
Ensure data governance, privacy and compliance (HIPAA, GDPR) throughout model development and deployment

Scientific Leadership & Collaboration
Partner with domain experts to define scientific questions, shape the ML roadmap and prioritize strategic data problems
Rapidly test hypotheses, ship prototypesMVPs and define evaluation metrics (accuracy, latency, interpretability, robustness, fairness)
Communicate complex technical concepts clearly to crossfunctional stakeholders and drive datadriven decision making

Mentorship & Best Practices
Provide technical leadership and mentorship to junior engineers and scientists
Foster best practices in code quality, testing, reproducibility and documentation
Publish highimpact research in peerreviewed journals or conferences

Required Qualifications

PhD in Computer Science, Bioinformatics, Computational Biology, Statistics or equivalent practical experience
8+ years applying MLAI to realworld problems in healthcare, life sciences, genomics or digital pathology
Proficiency in Python and deeplearning frameworks (PyTorch, TensorFlow or Keras)
Handson experience integrating LLMs andor computervision models into production pipelines
Strong communication skills with demonstrated crossfunctional leadership

Preferred Qualifications
Prior work with EHRLIMS data processing or bioinformatics pipelines
Publications or opensource contributions in biomedical AI ML
Familiarity with agent frameworks (e.g., LangChain, MCP) and automated decisionsupport workflows
Experience with vector databases and semantic search (Pinecone, Weaviate)
Handson expertise with AWS ML services, container orchestration (Docker, Kubernetes) and API development

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$178,900$223,650 USD

OUR OPPORTUNITY

Natera™ is a global leader in cellfree DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from worldclass institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https:www.natera.comnoticeofdatacollectioncaliforniaresidents

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
BBB announcement on job scams
FBI Cyber Crime resource page

Required profile

Experience

Level of experience: Senior (5-10 years)
Spoken language(s):
English
Check out the description to know which languages are mandatory.

Other Skills

  • Mentorship
  • Collaboration
  • Communication
  • Leadership

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