Director, Medical Evidence Generation, Neurology

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs.  With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. 

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. 

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

DIRECTOR, MEDICAL EVIDENCE GENERATION, NEUROLOGY

SUMMARY: 

The Director of Medical Evidence Generation, Neurology will be responsible for executing Ionis’ medical evidence generation strategy in the neurology therapeutic area. This role will also serve as the lead for the Medical Affairs Epidemiology function, serving as a cross-TA Epi resource. The role will involve working closely with cross-functional teams including Medical Affairs, Clinical Development, HEOR, and Commercial teams to design and conduct epidemiology studies/analyses, observational research studies, develop disease and product registries, and design and implement Phase 4 studies. This role will report to the Executive Director of Medical Evidence Generation.

RESPONSIBILITIES: 

• Lead Integrated Evidence Generation Planning (IEGP) for the assets in the Neurology TA.
• Design and execute evidence generation activities that will fill priority evidence gaps identified in asset-specific IEGPs.
• Serve as the hub of epidemiology data (cross-TA) for internal and external use, based on literature reviews or other sources.
• Design and lead observational research studies to evaluate real-world effectiveness, safety, and other outcomes.
• Develop and maintain disease and product registries, including collaborative registries with academic institutions, patient advocacy groups, or other external organizations.
• Design and implement Phase 4 study designs, including observational studies, to generate additional medical evidence for marketed products.
• Apply causal inference expertise to ensure robust analysis of observational data to support evidence-based decision-making.
• Collaborate with cross-functional teams including Medical Affairs, Clinical Development, HEOR, and Commercial teams to ensure that medical evidence generation activities are aligned with the overall business objectives.
• Present medical evidence to internal and external stakeholders, including at scientific conferences, and other relevant forums.
• Stay up-to-date with the latest developments in epidemiology, observational research, registry methodologies, Phase 4 study design, and advanced analytical methods, and incorporate them in Ionis’ medical evidence generation activities.

REQUIREMENTS:

• A PhD or Master’s degree in epidemiology, public health, or related field with at least 8 years of experience in the pharmaceutical industry.
• Extensive experience designing and leading observational research studies, including the use of real-world data.
• Demonstrated expertise in developing and maintaining disease and product registries.
• Strong knowledge of Phase 4 study design and implementation.
• Strong knowledge of causal inference methods, including propensity scores and instrumental variables.
• Strong analytical and problem-solving skills.
• Strong publication record.
• Excellent verbal and written communication and presentation skills.
• Ability to work collaboratively with cross-functional teams.
• Ability to work independently and manage multiple projects simultaneously.

If you are passionate about using medical evidence to improve health outcomes for patients and have appropriate qualifications, we encourage you to apply for this exciting opportunity.

Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS003808

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

Full Benefits Link: https://www.ionis.com/careers/working-at-ionis/#:~:text=our%20employee%20spotlight-,Benefits,-Employees%20are%20rewarded

The pay scale for this position is $233,662 to $260,000 

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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