Director of Architecture – Core Technology

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director of Architecture – Core Technology

What you will do

Let’s do this. Let’s change the world. In this vital role you will be Director of Architecture – Core Technology responsible for advising on the strategic design and implementation of the company’s Core Technology. This role ensures that the organization’s Core Technology aligns with business objectives, enabling scalability, security, reliability, and operational efficiency. The ideal candidate will bring deep technical expertise in cloud and on-premise environments, strong leadership skills, and a strategic approach to drive transformation, innovation, and continuous improvement.

Responsibilities:

• Defining and enforcing consistent Core Technology standards across several domains (incl. Cloud, Compute, Storage/Backup, Virtualization, Automation, Network) to ensure reliability, efficiency, and security.
• Leading transformation by planning and executing the transition to an Infrastructure-as-a-Platform capability, driving automation, scalability, and operational agility.
• Advancing new capabilities around the AI/ML Model lifecycle, AI/ML Core Technology, and High-Performance Computing (HPC) to meet evolving business needs.
• Develop standards to meet evolving business needs around new capabilities like AI/ML and High-Performance Computing (HPC).
• Ensuring Security Alignment – Collaborating closely with Security Architecture to embed security-by-design principles into all Core Technology capabilities.
• Advising Leadership on Strategy – Providing insights on infrastructure trends, risks, and opportunities to guide decision-making.
• Increasing efficiency by applying DevSecOps principles throughout the Core Technology lifecycle via automation and Infrastructure-as-Code.
• Seamless integration of Core Technology capabilities and processes into broader ecosystems such as Digital Asset Management and Financial Planning.
• Reducing risk exposure through standardized Core Technology architecture and globally adopted standard processes.
• Optimizing Costs and Performance – Establishing cost management best practices, including chargeback models, performance tuning, and service reliability.
• Mentoring and Coaching – Supporting architects and engineers in developing best practices and technical expertise.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The technology architectural professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of Computer Science Or Information Technology experience

Or

Master’s degree and 7 years of Computer Science Or Information Technology experience

Or

Bachelor’s degree and 9 years of Computer Science Or Information Technology experience

Preferred Qualifications:

• 10+ years of experience in IT Infrastructure/Core Technology architecture, with at least 5 years in a leadership role.
• Experience with road mapping and driving the transition of Infrastructure services into a Platform-as-a Service Core Technology capability
• Demonstrable experience designing and managing enterprise-level cloud and on-premise Core Technology solutions.
• Strong knowledge of cloud platforms (especially AWS), compute, virtualization, networking, and storage technologies.
• Hands-on experience with Core Technology automation principles and tools, Infrastructure-as-Code (IaC), and DevSecOps practices.
• Expertise in security standard processes, compliance frameworks (e.g., NIST, ISO 27001, SOC2), and disaster recovery strategies.
• Exceptional problem-solving and decision-making skills.
• Good communication skills with the ability to engage both technical and non-technical stakeholders.
• Good understanding of emerging technologies and such as AI/ML.
• Experience working in a highly regulated industry such as finance, healthcare, or government.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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