Curation Scientist Step II

Description

About Us

Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform.

Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike.

Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company.

Summary of Position

This is the second step of the Genetic Curation Scientist (GCS) career track. Compared to Step 1, GCS Step 2 has more responsibilities in research & development, must be approved by a laboratory director to perform del/dup analysis, and must be approved by a laboratory director to curate more complex case types such as large panels, exomes, etc.

GCS will be responsible for the research, investigation, and classification of genetic variants using a combination of our internal proprietary software, published scientific literature, and publicly available databases. GCS will determine the pathogenicity of DNA sequence variants found real-time in patients and will customize clinical report text in collaboration with laboratory directors and genetic counselors. GCS are also responsible for quality control, technical assessment, copy number analysis, and other interpretive components of molecular diagnostics as outlined in curation standard operating procedures.

Key Job Elements

• Perform quality control assessment for Next Generation Sequencing and other molecular diagnostic assays.
• Must be approved to perform del/dup analysis (“First Check”).
• Must be approved to perform large panel and/or exome sequencing curation.
• Classify detected variants according the internal and professional guidelines.
• Draft clinical lab report according to internal and professional standards; reports will be submitted to a laboratory director for final review and sign-out.
• Review literature and databases to evaluate gene-disease association.
• Review and update genetic variations based on new information.
• Support Client Services Department and Laboratory Genetic Counselors to respond to client requests for information on the interpretation of variants.
• Participate in research & development projects as they arise.

Qualifications

Knowledge/Experience

Preferred Experiences:

• Proven ability to critically read and interpret scientific literature.
• Strong computer, scientific, and organizational skills.
• Outstanding attention to detail and efficient work habits.
• Excellent communication (oral and written).
• Ability to work independently and as part of a team with self-motivation, adaptability, and a positive attitude.
• Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.

Minimum Qualifications:

• Ph.D. in Human Genetics or appropriately related field, or Masters of Genetic Counseling with strong molecular genetics background or previous DNA sequencing reporting experience.
• Familiarity with Mendelian genetics and a thorough knowledge of molecular genetics.
• One (1) year of experience as a GCS at Fulgent or equivalent experience at a different institution.

Supervisory Responsibilities

• None

Reports To

• Laboratory Director

Environment

Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term “qualified individual with a disability” means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position.

For California residents, please see the link below to access our CCPA Privacy Notice.

CCPA Privacy Notice for California Residents

https://tinyurl.com/FulgentCCPA

Please note that Fulgent (and its affiliated companies, including Inform Diagnostics and CSI Laboratories) does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Search firms or agencies without an applicable contract and/or express approval to recruit for the role in question — that choose to submit a resume or client information to our career page or to any employee of Fulgent — will not be eligible for payment of any fee(s), and any associated shared data will become the property of Fulgent.