Department Overview:
The OHSU Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. Driven by its mission to end cancer as we know it, the institute is building upon its expertise in targeted treatments for cancer as well as to advance the early detection of cancer when the disease is most treatable.
Every Knight Cancer employee is expected to embody our guiding principles:
- We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
- We SUPPORT each other—Respect leads to trust, which leads to excellence
- We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone
Function/Duties of Position:
This position supports assays run on the Nanostring GeoMx Digital Spatial Profiler system, including both clinical
and research tumor samples. The tasks for this position are as follows: 1) Prepare slides for multiplex antibody
incubations following a standard protocol. 2) Under guidance of a pathologist, select regions of interest for
collection of oligonucleotide barcodes. 3) Process the collected oligonucleotides for quantitation on the
Nanostring nCounter system. 4) Maintain laboratory supplies and manage inventory. 5) Track and manage general
sample workflow. In addition to these tasks, the position may help with routine immunostaining of cancer
specimens, other histology tasks, and tissue microarray construction.
This position requires skills in handling laboratory specimens (human and mouse), record keeping, laboratory
equipment maintenance and quality assurance. The ability to work with several computer systems is necessary.
An ability to identify cells and cell morphology at the light microscopic level is desirable. Experience in histology,
including sectioning and staining tissue sections, is also desirable but not essential. Molecular or cellular biology
knowledge/skills (PCR, Immunofluorescent imaging and/or cell culture) would be helpful.
This position requires following established protocols, communicating well and working effectively as part of a
team. The technician will interact with a variety of scientists and other staff, and is expected to keep the
laboratory in good working order, including maintaining supplies, prepare stock solutions, and keeping complete
and accurate records of all experiments. The position may allow some flexibility in work hours, including some
nights and weekends, but not work-from-home.
Key Resonsiblities:
- Nanostring GeoMx Digital Spatial Profiler support. Prepare and process slides of human and mouse tumor samples on the Nanostring DSP and use the Nanostring MAX nCounter system for data generation
- Workflow Development. Assist in antibody testing and other quality control assays, as well as cell culture.
- Maintain Laboratory. Track reagents and supplies, placing orders as needed. Track specimens through workflows.
- Data Analysis: Provide processed data to computational biologists or biostatisticians, helping to identify technical factors in data generation and processing and supporting development of biological conclusions that drive the next generation of research and advance human health.
- Career Development: Participate in appropriate activities that enhance general knowledge of or ability to do assigned work. This includes, but is not limited to, the following: attend classes, seminars, and other training forums; stay current in relevant literature; participate in staff meetings and other informational sessions; read vendor documentation as appropriate to position; interact with peers and other employees to receive and disseminate information.
Required Qualifications:
Education:
- Completion of a 2-year accredited program in Medical Laboratory Technician training plus MLT (ASCP) within 90 days of hire or AMT certification within 90 days of hire. Depending on date of training, different continuing education requirements will apply;
- OR Bachelor’s degree in a chemical or biological science and two years of Laboratory Technical Assistant training/experience performing standardized laboratory tests in the specialty area(s) in which high complexity testing will be performed; Depending on date of training, different continuing education requirements will apply.
Job Related Knowledge, Skills and Abilities:
- Must have interest in cancer research and read relevant literature
- Must be willing to perform all of the techniques described, with training
- Ability to prioritize multiple tasks at one time
- Excellent communication, analytical and organizational skills: both written and verbal
- Ability to work independently and as part of a team while being collaborative in resolving problems
- Intermediate skills with Microsoft Office (Excel, Outlook, Access, Word, and PowerPoint) on Window OS.
- Ability to accurately type 60wpm
- Must have demonstrated excellent customer service skills both on the phone and in person
- Must possess energy and drive to coordinate multiple projects simultaneously
Preferred Qualifications:
Education:
- Certification in Histotechnology
- Bachelor’s Degree (4yr) with major courses in biology or related field and 1-2 years of laboratory work.
Experience:
- 1-year experience in histology, including preparation and staining microscope slides.
- Relevant coursework in tissue pathology
- 1-2 years of experience working in a laboratory, including handling reagents, pipetting, running assays and collecting data
Job Related Knowledge, Skills and Abilities:
- At least 6 months of work experience in a professional, team-oriented research setting (wet or dry lab) ·
- Deep understanding of immunohistochemistry
- Advanced understanding of slide scanning and imagining software
Additional Details:
Apply online. Please be sure to upload a Cover Letter and Resume/CV.
We offer a variety of benefits on top of joining a thriving organization:
- Medical, dental and vision coverage at no or low cost to employees
- Covered 100% for full-time employees and 88% for dependents
- Several retirement plans to choose from with contributions from OHSU
- 104 hours of vacation time per year (increases over time)
- 96 hours of sick leave a year (prorated for part-time employees)
- Commuter subsidies
- Tuition reimbursement
- Access to group life insurance, disability insurance and other supplemental benefits
- Annual Raises
- Growth/Development Opportunities
- Employee discounts to local and major businesses
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All are welcome:
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.
