Executive Director, Commercial Strategy & Planning

Syndax Pharmaceuticals is looking for an Executive Director, Commercial Strategy & Planning

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. Syndax Pharmaceuticals is a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies.

The Role:

 Syndax is seeking an experienced and innovative Executive Director, Commercial Strategy & Planning with a proven track record in oncology commercial product development and developing and launching assets in the U.S. and globally. This senior-level position will guide the commercial strategy across the Syndax Menin portfolio. This role is essential to driving Syndax's growth by optimizing our early stage and lifecycle commercial strategy and ensuring successful product launches that align with the company’s mission to develop transformative therapies for patients in need.  Reporting directly to the VP, Customer Engagement, the successful candidate will be able to bring significant depth and breadth of experience to positively impact the strategic value to the program, rapidly and effectively, in partnership with the cross-functional asset team. The role will have high visibility to executive level leadership.

Key Responsibilities: 

• A key leader of the Asset Strategy Team, member of the Customer Engagement Leadership Team, and representative of the Syndax commercial team across the US and key international markets, responsible for providing commercial input into the Integrated Strategic Plan for strategic assets.
• Key contributor in the development of the Menin portfolio strategy and lifecycle activities including indication sequencing and prioritization.
• Commercial lead for development and implementation of integrated strategic plans, aligning short- mid- and long-term goals across the organization.
• Support the creation of development plans that achieve a unique value proposition to ensure competitive differentiation in target markets.
• Consider patient-centric commercialization strategies by understanding patient journeys and applying insights into actionable strategies.
• Lead commercialization strategies for pipeline assets, from clinical development through commercialization.
• Identify and analyze market trends, competitor activities, and emerging therapies to refine pipeline marketing efforts.
• Partner with R&D, clinical, medical, and commercial teams to incorporate market feedback and ensure alignment of pipeline programs with market needs.
• Drive asset-specific marketing strategies to maximize product value and market potential.
• Develop and implement lifecycle management plans for each asset, including indication expansion, positioning shifts, and competitive readiness.
• Utilize data-driven insights and market research to assess potential asset opportunities and challenges, informing asset prioritization and resource allocation.
• Collaborate with medical affairs, HEOR, and market access teams to optimize asset strategies that synthesize and address payer, provider, and patient needs.
• Lead the development of launch strategies for new products, including market entry strategies, pricing, and reimbursement planning.
• Conduct in-depth market assessments and revenue forecasts for new product candidates to guide strategic decision-making.
• Established relationships with key opinion leaders (KOLs), academic/community centers, advocacy groups, and stakeholders to gather insights and inform new and established product planning.
• Ensure that commercial strategies for new products align with Syndax’s broader portfolio strategy and meet regulatory requirements.
• Lead by influence and demonstrate collaborative behaviors to foster cross-functional way of working, both with the teams and with the functions.

Desired Experience/Education and Personal Attributes:

• Bachelor’s degree in Business, Marketing, or Life Sciences required. MBA or advanced degree in a related field preferred.
• Minimum 15 years of progressive experience in biopharmaceutical commercialization.
• Minimum of 7 years experience leading strategic initiatives within commercial functions.
• Oncology experience required; hematology experience preferred.
• Proven track record in leading strategic commercialization in the U.S. and ex U.S. markets.
• Experience as part of a cross-functional program team supporting early- and late-stage programs through regulatory milestones (NDA/BLA), life cycle management and geographical expansion.
• Extensive experience in leading product launches and lifecycle management.
• Strong understanding of the oncology/hematology market landscape, including regulatory requirements, payer dynamics, and competitor positioning.
• Superior strategic thinking, data-driven decision-making, and analytical skills.
• Excellent communication and leadership abilities, with the capability to influence cross-functional teams and senior leadership.
• Ability to navigate and thrive in a fast-paced, highly dynamic environment.

Location: Syndax has offices in Waltham, MA and New York City.

About Syndax:
Syndax Pharmaceuticals is a commercial stage biopharmaceutical company developing an innovative pipeline of cancer therapies. Highlights of the Company's pipeline include revumenib a highly selective menin inhibitor, and Niktimvo™ (axatilimab-csfr), a monoclonal antibody that blocks the colony stimulating factor 1 (CSF-1) receptor. Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment for both revumenib and Niktimvo. For more information, please visit www.syndax.com/ or follow the Company on X (formerly Twitter) and LinkedIn.

Syndax Pharmaceuticals is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

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