Director, High Throughput Process Automation

The Director/ HTPA (High Throughput & Process automation), as a critical team leader of the ERPD (Early Research Process Development) group in GTCOE (Genetic Therapies Center of Excellence) will support Sarepta’ pipeline of cutting-edge recombinant AAV viral vector-based therapies. S/he will continue to build the high throughput and process automation capabilities in the process & analytical development with the team of HTPD scientists and research associates to accelerate the timeline to develop the cutting-edge technology to produce and analyze the high-quality recombinant AAV vectors. S/he will work in a highly interdisciplinary environment and be expected to communicate effectively and productively with the research organization, late-stage PD group, manufacturing group, regulatory, quality, and other cross-functional organizations as needed to achieve rigorous scientific, technical, and product quality expectations.

Primary Responsibilities Include:

• Build and optimize the existing high throughput platforms and innovative process automation in process & analytical development
• Lead the automation scientists and independently implement solutions for high throughput screens using a variety of automation equipment
• Evaluate, develop, and implement new technologies to Sarepta's Process & Analytical Development and Manufacturing platforms
• Initiate investigation of new analytical approaches to a wide range of problems using scientific theory and technical literature
• Explore the process characterization with the liquid automatic handler as a qualified scale-down model
• Work closely with the team leaders in the ERPD organization and Internal and External research teams to enable platform acceleration
• Actively participate in various early research programs and cross-functional team meetings to play a key role as a subject matter expert for the process and technology
• Provide guidance and direction to his/her direct reports; establishes goals, defines roles, supports career development, and manages performance
• Ensure accurate and timely analysis of data to support preparation and submission of process and analytical method development reports
• Support regulatory agency questions and prepare the data for regulatory interaction as needed
• Work seamlessly with cross functional stakeholders to help advance the AAV vector production portfolios

Desired Education and Skills: 

• Advanced degree (MS or PhD) in Biochemistry, Bioengineering, Chemical Engineering, or a related field is with 10+ years of relevant working experience within biotechnology/ pharmaceutical industries is required
• Extensive experience and excellent knowledge in high throughput/ process automation and programming are required
• Hands-on experience with the liquid automatic handler (Tecan or Hamilton) is required
• Experience in managing teams of 5+ scientists/ engineers are required
• Experience in process and/or analytical development for viral vectors or other biologics is required
• Experience with gene therapy with recombinant AAV vectors is a plus
• Excellent written and verbal communication skills are required
• Proven record of successfully planning experiments and executing projects in collaboration with internal or external stakeholders
• Strong team player who works closely and effectively with cross-functional organization
• Proven ability to hire & integrate new talent into the organization, manage performance, develop people, and model the company’s core values and culture

This position requires work on site at one of Sarepta’s facilities in the United States.

Candidates must be authorized to work in the U.S.

Sarepta Therapeutics offers a competitive compensation and benefit package.

Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.