Senior Research Associate, Protein Separations & CMC

At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

Role

Our team is responsible for supporting CMC (Chemistry, Manufacturing & Controls) development through all stages of clinical progress. For pre-clinical stage programs, we constantly seek to improve our capabilities on screening and defining efficient strategies of antibody purification. For late clinical stage programs, we perform downstream process (DSP) characterization to define suitable and robust operating ranges, mostly for chromatography and TFF (Tangential Flow Filtration) steps. We constantly seek to improve on existing process and analytical techniques and to introduce new technologies for process development and characterization.

 

Responsibilities
 

• With your up-to-date knowledge and broad experience of chromatography, antibody characterization and biochemistry, will plan and perform protein separation experiments of antibody products.
• You constantly contribute to the optimization and innovation of our team.
• You support software applications like Empower and Unicorn.
• You work closely with CMC colleagues, scientists and other research associates in the international project teams.
• You document results in presentations and written reports.

Requirements

You are keen and motivated to use your up-to-date knowledge and experience with protein separation techniques to strengthen our team. You are an expert in protein purification. You are keen on pro-active and solution-oriented. You are precise and accurate in the execution of experiments and in the documentation of the results. You have good communication skills and are able to deal with changing priorities and unexpected workload. You like to work in a team but you are also capable of working independently.

In addition, you meet the following professional requirements:

• You have a completed HLO/BSc or MSc education or equivalent. Applicants holding a PhD are considered overqualified and will not be considered.
• You have at least 3 years of relevant work experience.
• You have proven experience of CMC process development.
• A successful candidate will be a self-motivated individual who is well versed in techniques including chromatography (PA, IEX, HIC etc.), filtration (including TFF), high-throughput screening, design of experiment (DoE) and data analysis.
• You can work with tight deadlines and are capable of running several projects in parallel and adjust priorities appropriately.
• You are a strong team player and collaborate effectively with internal and external parties in project and expert teams.
• You are motivated by delivering high quality output and are used to working according to a quality system.
• You have good relational and communication skills in English, as it is Genmab's main language.

About You

• You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
• You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with diverse backgrounds
• You are determined to do and be your best and take pride in enabling the best work of others on the team
• You are not afraid to grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose guiding its unstoppable team to strive towards improving the lives of patients through innovative and differentiated antibody therapeutics. For more than 20 years, its passionate, innovative and collaborative team has invented next-generation antibody technology platforms and leveraged translational research and data sciences, which has resulted in a proprietary pipeline including bispecific T-cell engagers, next-generation immune checkpoint modulators, effector function enhanced antibodies and antibody-drug conjugates. To help develop and deliver novel antibody therapies to patients, Genmab has formed 20+ strategic partnerships with biotechnology and pharmaceutical companies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO™) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with locations in Utrecht, the Netherlands, Princeton, New Jersey, U.S. and Tokyo, Japan. 
 

Our commitment to diversity, equity, and inclusion

We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website. 

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website https://www.genmab.com/privacy.

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.